We're inviting you to take part in a study for patients who have Ulcerative Colitis to evaluate the effect of the investigational study drug in treating the symptoms of UC. All study-related visits, tests, care, and study drug will be provided at no cost. In addition, compensation for study-related travel may be provided. Health insurance is not required to participate.
The study will be evaluating the efficacy of an investigational study drug for treating the symptoms of UC. Volunteers who qualify to take part in the study may receive compensation for their time and travel expenses.
Ulcerative Colitis (UC) is an inflammatory bowel disease that causes ulcers (sores) and painful inflammation in the digestive tract. UC is a condition that develops over time and affects the innermost lining of the large intestine and rectum. The ulcers may produce blood or pus and mucous and can cause abdominal pain and the need to frequently empty your colon.
Ulcerative Colitis can cause debilitating symptoms and sometimes life-threatening complications. Many people experience symptoms– occasionally with long periods of remission. Signs and symptoms may include:1
The cause of Ulcerative Colitis remains unknown. It is the result of several factors that are not yet well understood. Abnormal immune response, genetics, and environmental factors can all contribute to UC. Although diet and stress were previously suspected, research has since ruled this out stating that diet and stress may aggravate the condition but are not a cause.
Ulcerative Colitis may be triggered by an interaction between a virus or bacterial infection in the colon and the body’s immune response. In UC patients, the inflammation persists long after the immune system should have finished its job. The body continues to send white blood cells into the lining of the intestines, where the inflammation and ulcers form.2
Although there is no cure for Ulcerative Colitis, there are treatments that may help improve symptoms of the condition. Most treatments usually involve drug therapies or surgery. The course of action typically depends on the severity of the condition and is evaluated and administered by a specialty physician.3
Current medical treatments for Ulcerative Colitis include anti-inflammatory therapies, immune suppressants, and a new category of medications called biologic therapies. Biologic therapies target specific immune system markers to combat various medical conditions.4 The investigational medication in this study is a biologic therapy that targets an immune protein associated with tissue inflammation.
The Ulcerative Colitis Studies are looking to see how well an investigational medication works in treating the symptoms of UC.
A Clinical Research Study (also called a clinical trial) is a medical study that helps answer important questions about an investigational drug or device, such as: does it work, or how effective is it compared to another drug/device?
All medications must be tested in clinical research studies before they can be approved by regulatory authorities for doctors to prescribe to patients. Without people taking part in these studies, we would have no new treatments. The volunteers who participate in clinical research studies play a major role in helping to advance medicine.
The Ulcerative Colitis Studies will include various visits to a study clinic in your area and follow up phone calls at designated times.
All study-related care is provided at no cost to you. You do not need health insurance to participate.
Volunteers who take part in the study may receive compensation for their time and travel.
Participation is entirely voluntary. Even if you decide to take part in this study, you can change your mind about participating at any time.
There is no cost to participate in the Ulcerative Colitis Studies. If you qualify, the investigational drug, study-related tests, assessments, and visits will be provided to you at no cost. You will receive study-related care throughout the study from a team of experienced doctors and nurses.
Volunteers who take part in the studies may be compensated for their time and travel. Please discuss this with the study team when they contact you.
What happens if I Sign Up? If you sign up, we will match you to a study clinic in your area that is seeking participants or notify you when one becomes available. They will contact you to explain more about the study before you make your decision about participating. You will attend an in-person visit where the study clinic will help determine if you qualify and if the study is right for you.
If you think you might like to join the Ulcerative Colitis Study or would like more information, please enter your information below so we can see if you qualify and can contact you about the study.
The Ulcerative Colitis Studies will include patients with Ulcerative Colitis and will be conducted at various study sites in the USA. All study-related care will be provided by specialty physicians and a dedicated study team.
If you qualify for a study, you will visit a study site in your area throughout the study.
The Ulcerative Colitis Studies will be evaluating the effectiveness of an investigational study drug in treating the symptoms of UC. Volunteers who qualify to take part in the study may receive compensation for time and travel expenses.
Participants may be eligible to take part in the Ulcerative Colitis Studies if you:
All study-related care will be provided by a team of experienced doctors and nurses.